A series of novel 4-substituted-N-(phenyl(2,4,5-triphenyl-1H-imidazol-1-yl)methyl)benzenamine have been synthesized and evaluated for antidiabetic activity on male wistar rats by oral glucose tolerance test (OGTT) method using pioglitazone as standard. The newly synthesized compounds have been characterized by IR, mass and 1H NMR spectroscopic studies and report of them supports the structures of compounds. Comparison of data was performed by one way ANOVA followed by post test, dunnett’s multiple comparision tests.
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